Gender transition hormones cause brain swelling in children

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In the United States, where the trend is to allow and even encourage children, including young children, to undergo treatment for gender reassignment, the Food and Drug Administration (FDA), the country’s food and drug regulatory agency, has reported that the use of puberty blockers can cause brain swelling, loss of vision and serious risks for children.

According to FDA officials, six girls ages 5 to 12 who used the puberty-blocking product — gonadotropin-releasing hormone (GnRH) — developed pseudotumor cerebri, a condition whose symptoms are similar to those of a brain tumor.

However, this is not the case. In the case of pseudotumor, there is, yes, a higher pressure of the fluid system inside the skull, but imaging tests do not detect the presence of tumors, nor the enlargement of the brain cavities or any other anatomical cause.

“Five girls were undergoing treatment for precocious puberty and one was undergoing treatment for transgenderism,” FDA officials said in a report published by American Academy of Pediatrics (AAP). “The onset of symptoms of pseudotumor cerebri ranged from three to 240 days after starting treatment with GnRH.”

The most common symptoms were visual disturbances, headaches and vomiting, but there were also increased blood pressure, cerebral edema and abducens neuropathy (paralysis of an ocular nerve).

An FDA spokesperson said the cases were considered clinically serious and that the agency had mandated the placement of a warning on GnRH-based products approved for pediatric patients. Technicians still don’t know how the substance causes the pseudotumor, but as the risk is serious, specific labeling should be done.

Puberty blockers and hormones have come under fire again after President Joe Biden’s Assistant Secretary of Health Rachel Levine said the US should ensure young people have access to so-called “gender-affirming care.” as published West.

However, the Florida Department of Health argued the opposite of Levine’s claims, saying that due to the lack of conclusive evidence and the potential for irreversible, long-term effects, doctors should not prescribe puberty blockers or hormone therapy to minors. of 18 years.

“Based on the evidence currently available, ‘encouraging mastectomy, ovariectomy, uterine extirpation, penile deficiency, tracheal hair removal, prescribing hormones that are at odds with the child’s genetic makeup or puberty blockers are current clinical practices. an unacceptably high risk of harm,'” the Florida Department of Health wrote in a memo.

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